1. About amlodipine
Amlodipine is a medicine used to treat high blood pressure (hypertension).
If you have high blood pressure, taking amlodipine helps prevent future heart disease, heart attacks and strokes.
Amlodipine is also used to prevent chest pain caused by heart disease (angina).
This medicine is only available on prescription. It comes as tablets or as a liquid to swallow.
2. Key facts
- Amlodipine lowers your blood pressure and makes it easier for your heart to pump blood around your body.
- It’s usual to take amlodipine once a day. You can take it at any time of day, but try to make sure it’s around the same time each day.
- The most common side effects include headache, flushing, feeling tired and swollen ankles. These usually improve after a few days.
- Amlodipine can be called amlodipine besilate, amlodipine maleate or amlodipine mesilate. This is because the medicine contains another chemical to make it easier for your body to take up and use it. It doesn’t matter what your amlodipine is called. They all work as well as each other.
- Amlodipine is also called by the brand names Istin and Amlostin.
3. Who can and cannot take amlodipine
Amlodipine can be taken by adults and children aged 6 years and over.
Amlodipine is not suitable for some people.
To make sure amlodipine is safe for you, tell your doctor if you:
- have had an allergic reaction to amlodipine or any other medicines in the past
- are trying to get pregnant, are already pregnant or you’re breastfeeding
- have liver or kidney disease
- have heart failure or you have recently had a heart attack
4. How and when to take it
Take amlodipine exactly as your doctor has told you, and follow the directions on the label. If you’re not sure, check with your doctor or pharmacist.
It’s usual to take amlodipine once a day. You can take amlodipine at any time of day, but try to make sure it’s around the same time every day.
How much to take
Amlodipine comes as 5mg and 10mg tablets.
Depending on why you’re taking amlodipine, the usual starting dose is 5mg once a day.
If the starting dose isn’t working well enough (your blood pressure doesn’t lower enough, or your angina isn’t controlled), you may need to increase your dose to 10mg.
To decide the correct dose for you in the longer term, your doctor will check your blood pressure to make sure it’s not too high or too low. They’ll also ask if you’re getting any side effects from the medicine.
Doses may be lower for children.
How to take it
You can take amlodipine with or without food.
Swallow amlodipine tablets whole with a drink of water. If it’s easier, you can dissolve the tablets in a glass of water, but you must drink it all straight away if you do this.
Do not eat or drink lots of grapefruit or grapefruit juice while you’re taking this medicine. Grapefruit can increase the concentration of amlodipine in your body and worsen side effects.
If you’re taking amlodipine as a liquid, it’ll come with a plastic syringe or spoon to help you measure out the right dose. If you don’t have one, ask your pharmacist for one.
Do not use a kitchen teaspoon as it will not give the right amount of medicine.
Do not mix the liquid with food or other drinks before taking it.
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